REVERSES ALCOHOL-INDUCED HEPATIC STEATOSIS
December 21, 2023POTENT ANTIHYPERTENSIVE
December 21, 2023- Improved arterial compliance by a novel advanced glycation end-product crosslink breaker
- Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes
- Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension
- The effect of an advanced glycation end-product crosslink breaker and exercise training on vascular function in older individuals: a randomized factorial design trial
- Reversal of chaperone activity loss of glycated αA-crystallin by a crosslink breaker
- Reversal Of Lens Protein Crosslinking And Aggregation By A Novel crosslink breaker
- The effect of alagebrium chloride (ALT-711), a novel glucose cross-link breaker, in the treatment of elderly patients with diastolic heart failure
- A breaker of advanced glycation end products attenuates diabetes-induced myocardial structural changes
- The Effect of the AGE crosslink breaker ALT-711 on Accommodation, Outflow Facility, IOP, and Anterior Segment Morphology
- Advanced Glycation Endproduct “AGE” Accumulation in Elderly Hypertensive Canines: Correlation with Effects of AGE crosslink breaker
- The thiamine analogue and advanced glycation endproducts crosslink breaker ALT-711 does not interfere with transketolase activity
- Effects of alagebrium, an advanced glycation end‐product breaker, in patients with chronic heart failure: study design and baseline characteristics of the BENEFICIAL …
- An agent cleaving glucose-derived protein crosslinks in vitro and in vivo
- Effects of alagebrium, an advanced glycation endproduct breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
- Therapeutic potential of breakers of advanced glycation end product–protein crosslinks
- Evaluation in vitro of AGE-crosslinks breaking ability of rosmarinic acid
- Advanced glycation end-products (AGEs): a novel therapeutic target for osteoporosis in patients with rheumatoid arthritis
- … and clinical improvements among patients with advanced heart failure treated with Alagebrium (a novel oral advanced glycation end-product crosslink breaker)
- Current therapeutic interventions in the glycation pathway: evidence from clinical studies
- The Effect of Advanced Glycation End Products (AGE) breaker, Alagebrium on the Cardiac Structural and Functional Change in Type I Diabetic Rat Model
- Evaluate the effect of Withania somnifera methanolic extracts as in-vitro antiglycating agents
- C16, a novel advanced glycation endproduct breaker, restores cardiovascular dysfunction in experimental diabetic rats1
- The breakdown of pre‐existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
- Effects of Advanced Glycation End-Product Inhibition and Protein Cross-Link Breaking in Diabetic Rats
- The putative antiglycation agent phenacylthiazolium bromide suppresses cellular triosephosphate accumulation in model hyperglycaemia in vitro by stimulating the …
- Alagebrium attenuates methylglyoxal induced oxidative stress and AGE formation in H9C2 cardiac myocytes
- Pharmacological therapy of age-related macular degeneration based on etiopathogenesis
- Effect of the AGE-breaker alagebrium on plasma and tissue advanced glycation end-products and sRAGE
- Extracellular glycation crosslinks: prospects for removal
- Factors influencing crosslink formation in muscle tissue
- Effect of advanced glycation end‐products (AGE) lowering drug ALT‐711 on biochemical, vascular, and bone parameters in a rat model of CKD‐MBD
- Advanced glycation endproduct crosslinking in the cardiovascular system: potential therapeutic target for cardiovascular disease
- Effects of alagebrium, an AGE breaker, on exercise tolerance and cardiac function in patients with chronic heart failure
- Effect of non-antihypertensive drugs on endothelial function in hypertensive subjects evaluated by flow-mediated vasodilation
- Treating diastolic heart failure with AGE crosslink breakers: thinking outside the heart failure box
- Novel therapies for diabetic kidney disease: storied past and forward paths
- Aldose reductase inhibition ameliorates the detrimental effect of estrogen replacement therapy on neuropathology in diabetic rats subjected to transient forebrain …
- Novel in Vitro Modification of Bone for an Allograft with Improved Toughness Osteoconductivity
- Gut microbiome-derived metabolite trimethylamine N-oxide induces aortic stiffening and increases systolic blood pressure with aging in mice and humans
- Effect of cysteine on methylglyoxal-induced renal damage in mesangial cells
- Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes
- Cardiovascular Complications
- Staphylococcus aureus Biofilm Inhibiting Activity of Advanced Glycation Endproduct crosslink Breaking and Glycation Inhibiting Compounds
- crosslink breakers: a new approach to cardiovascular therapy
- Alagebrium: benefit on peripheral arteries
- Advanced glycation end-products in chronic heart failure
- The effect of advanced glycation end products (AGE) breaker, alagebrium on the cardiac structural and functional change in type I diabetic rat model
- Phenotypic transitions and fibrosis in diabetic nephropathy
- Heart-Kidney Connection: Myocardial Infarction Induces Renal Cortical and Medullary Fibrosis and Activation of Renal Molecular Remodeling in the Absence of Heart …
- Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage
- Diversity in management of heart failure patients
- Uncoupled Nitric Oxide Synthase Leads to Diastolic Dysfunction Irrespective of Blood Pressure
- The Effect of Breaking Advanced Glycation End-Products, With or Without Exercise Training on the Cardiovascular Effects of Aging
- Skin autofluorescence, 5-year mortality, and cardiovascular events in peripheral arterial disease: all that glitters is surely not gold
- Getting better without AGE: new insights into the diabetic heart
- The role of collagen crosslinks in ageing and diabetes-the good, the bad, and the ugly
- Vascular aging: from molecular mechanism to clinical significance
- Cleaving effect of pomegranate (Punica granatum) extract on crosslink derived from advanced glycation endproducts
- Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness
- Pyridoxal phosphate prevents progression of diabetic nephropathy
- The AGE of the matrix: chemistry, consequence and cure
- Dyssynchrony in Regional Left Ventricular Systolic Function in Light Chain Amyloidosis: Assessment Using Novel 4D Echocardiography
- Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
- Cardiovascular and renal effects of a collagen cross-link breaker (ALT 711) in adult and aged spontaneously hypertensive rats
- Hyperglycemia and arterial stiffness: the atherosclerosis risk in the communities study
- Fracturing Carbonate Reservoirs: Acidising Fracturing or Fracturing with Proppants?
- Alagebrium chloride protects the heart against oxidative stress in aging rats
- The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy
- Arterial stiffness: a focus on vascular calcification and its link to bone mineralization
- Advanced glycation end products, oxidative stress and diabetic nephropathy
- Diabetic nephropathy: important pathophysiologic mechanisms
- Advanced glycation end products in health and disease
- EFFECT OF AGE ON SHEAR MODULUS OF SKELTAL MUSCLE
- A review on prevention of glycation of proteins: Potential therapeutic substances to mitigate the severity of diabetes complications
- Targeting advanced glycation with pharmaceutical agents: where are we now?
- Inhibition of renin-angiotensin system and advanced glycation end products formation: a promising therapeutic approach targeting on cardiovascular diseases
- Therapeutic interventions for advanced glycation-end products and its receptor-mediated cardiovascular disease
- The inhibition of advanced glycation end products by carnosine and other natural dipeptides to reduce diabetic and age‐related complications
- The role of AGE/RAGE signaling in diabetes-mediated vascular calcification
- AGE-breaker ALT-711 plus insulin could restore erectile function in streptozocin-induced type 1 diabetic rats
- Advanced glycation/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults
- Assessing the potential of carboxylic acids as inhibitors of glycation
- N-phenacylthiazolium bromide reduces bone fragility induced by nonenzymatic glycation
- Repairing extracellular aging and glycation
- Potential new therapeutic agents for diabetic kidney disease
- Serum carboxymethyl–lysine, an advanced glycation end product, is associated with increased aortic pulse wave velocity in adults
- Diabetes and advanced glycation endproducts
- Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart
- Causes and characteristics of diabetic cardiomyopathy
- Advanced glycation and retinal pathology during diabetes
- AGEs and their interaction with AGE-receptors in vascular disease and diabetes mellitus. I. The AGE concept
- Pimagedine: a novel therapy for diabetic nephropathy
- Blockade of diabetic vascular injury by controlling of AGE-RAGE system
- Advanced glycation end-product cross-link breakers: a novel approach to cardiovascular pathologies related to the aging process
- Alagebrium (ALT-711) Attenuates Gastric Aspiration Induced Pulmonary Inflammatory Response In Mice Fed With High AGE Diet
- The putative role of methylglyoxal in arterial stiffening: A review
- Receptor for advanced glycation end products (RAGE): novel biomarker and therapeutic target for atrial fibrillation
- The effects of advanced glycation end products (AGEs) on dermal wound healing and scar formation: a systematic review
- Advanced glycation end-products and arterial stiffness in hypertension
- Role of AGEs in diabetic nephropathy
- TRC4186, a novel AGE-breaker, improves diabetic cardiomyopathy and nephropathy in Ob-ZSF1 model of type 2 diabetes
- The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin‐induced diabetic rats: Preventive versus curative …
- Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links
- Advanced glycation end products in renal failure: an overview
- Causative or associative: A critical review of the role of advanced glycation end-products in bone fragility
- Nitric oxide, oxidative excess, and vascular complications of diabetes mellitus
- Advanced glycation end products and diabetic complications
- Hydralazine inhibits rapid acrolein-induced protein oligomerization: role of aldehyde scavenging and adduct trapping in cross-link blocking and cytoprotection
- Republished paper: arterial stiffness in chronic kidney disease: causes and consequences
- The multiple faces of RAGE–opportunities for therapeutic intervention in aging and chronic disease
- Large artery stiffness and brain health: Insights from animal models
- Effect of Korean red ginseng on arterial stiffness in subjects with hypertension
- Therapeutic interventions in the glyc (oxid) ation pathway
- Novel therapeutics for diabetic micro-and macrovascular complications
- Heart failure with preserved ejection fraction: emerging drug strategies
- Effect of Cirsium japonicum Flower Extract on Skin Aging Induced by Glycation
- Advanced glycation of apolipoprotein AI impairs its anti-atherogenic properties
- The role of advanced glycation end-products and their receptor on outcome in heart failure patients with preserved and reduced ejection fraction
- Study on the nonenzymatic glycation of nucleosides/nucleotides and proteins with sugars: An in vitro investigation of advanced glycation endproducts (AGEs) …
- AGEs impair Kv channel-mediated vasodilation of coronary arteries by activating the NF-κB signaling pathway in ZDF rats
- Protein glycation during aging and in cardiovascular disease
- Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells—protection by carbonyl scavengers
- The role of collagen metabolism in CKD-associated arterial senescence: underestimated and underappreciated
- Protein crosslinking by the maillard reaction with ascorbic acid and glucose
- Advanced glycation endproducts and plaque instability: a link beyond diabetes
- An update on advanced glycation endproducts and atherosclerosis
- Skin autofluorescence, a marker for advanced glycation end product accumulation, is associated with arterial stiffness in patients with end-stage renal disease
- Advanced glycation endproducts (AGEs): pharmacological inhibition in diabetes
- Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis
- AGEs and cardiovascular diseases in patients with end-stage renal diseases
- Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease
- Glucose, Glycation, and RAGE: Implications for Amplification of Cellular Dysfunction in Diabetic Nephropath: y
- The role of advanced glycation in the pathogenesis of diabetic retinopathy
- Does accumulation of advanced glycation end products contribute to the aging phenotype?
- Potential clinical utility of advanced glycation end product cross-link breakers in age-and diabetes-associated disorders
- Emerging therapies for chronic kidney disease: what is their role?
- Effects of alagebrium, an AGE breaker, in patients with chronic heart failure: study design and baseline characteristics of the BENEFICIAL trial
- Low adipocyte IRS-1 protein expression is associated with an increased arterial stiffness in non-diabetic males
- Advanced glycation end products and schizophrenia: A systematic review
- Pharmacological control of receptor of advanced glycation end-products and its biological effects in psoriasis
- Physical properties of anionic poly (ε-caprolactam) synthesized in the presence of calcium chloride
- AGE-RAGE axis blockade in diabetic nephropathy: current status and future directions
- Association of pulse wave velocity with vascular and valvular calcification in hemodialysis patients
- Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension
- Advanced glycation end products and their circulating receptors and level of kidney function in older community-dwelling women
- Methylglyoxal and advanced glycation endproducts: new therapeutic horizons?
- Functional effects of alagebrium (alt-711)–isolated rat carotid artery
- The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase
- Advanced glycation: an important pathological event in diabetic and age related ocular disease
- Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications
- Oxidative stress and aging: is methylglyoxal the hidden enemy?
- Phase I clinical studies of the advanced glycation end-product (AGE)-breaker TRC4186: safety, tolerability and pharmacokinetics in healthy subjects
- Regulation of advanced glycation end product (AGE)-receptor (RAGE) system by PPAR-gamma agonists and its implication in cardiovascular disease
- Multi-User Publishing in the Web: DReSS, A Document Repository Service Station
- Current perspectives in diastolic dysfunction and diastolic heart failure
- Methylglyoxal displays colorectal cancer-promoting properties in the murine models of azoxymethane and CT26 isografts
- Aldose reductase pathway inhibition improved vascular and C-fiber functions, allowing for pressure-induced vasodilation restoration during severe diabetic …
- Modulation of α‐crystallin chaperone activity: A target to prevent or delay cataract?
- Impaired left ventricular relaxation in type 2 diabetic rats is related to myocardial accumulation of Nɛ‐(carboxymethyl) lysine
- Optimal treatment of hypertension with diastolic heart failure
- Agents in development for the treatment of diabetic nephropathy
- How important and how treatable is vascular stiffness as a cardiovascular risk factor in renal failure?
- Nephrin loss in experimental diabetic nephropathy is prevented by deletion of protein kinase C alpha signaling in-vivo
- Alagebrium and complications of diabetes mellitus
- Advanced glycation endproducts and osteoarthritis
- Role of advanced glycation end products in diabetic neuropathy
- Do diabetes and hypertension interact to accelerate vascular ageing?
- Drug therapy for the cardiac complications of diabetes
- Vascular mechanics in decellularized aortas and coronary resistance microvessels in type 2 diabetic db/db mice
- Molecular determinants of heart failure with normal left ventricular ejection fraction
- Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein AI
- Quinapril treatment abolishes diabetes-associated atherosclerosis in RAGE/apolipoprotein E double knockout mice
- Impact of age and hyperglycemia on the mechanical behavior of intact human coronary arteries: an ex vivo intravascular ultrasound study
- Preferential stiffening of central over peripheral arteries in type 2 diabetes
- A short-term admission improved brachial–ankle pulse wave velocity in type 2 diabetic patients
- New drugs under development for cardiovascular prevention
- The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium
- Arterial stiffness and wave reflections in relation to plasma advanced glycation end products in a Chinese population
- Cellular mechanisms and consequences of glycation in atherosclerosis and obesity
- Karl D. Nolph state of the art lecture: feasible and future options for salvation of the peritoneal membrane
- Heart Failure with Preserved Ejection Fraction
- Glycation: Receptor for Advanced Glycation Endproducts and Diabetic Nephropathy
- Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines
- Arterial stiffening: Causes and consequences
- Heart failure and diabetes mellitus: epidemiology and management of an alarming association
- Discovery of Anti-Glycation and AGEs breaker Agents and Study of their Mechanism of Action
- Jakyakgamcho-tang and its major component, Paeonia lactiflora, exhibit potent anti-glycation properties
- Clinical trials update from the European Society of Cardiology Heart Failure Meeting 2010: TRIDENT 1, BENEFICIAL, CUPID, RFA‐HF, MUSIC, DUEL, handheld BNP …
- Alteration of pressure-induced vasodilation in aging and diabetes, a neuro-vascular damage
- Targeting matrix remodeling in cardiac hypertrophy and heart failure
- The role of advanced glycation end products in retinal ageing and disease
- Targeting AGEs signaling ameliorates central nervous system diabetic complications in rats
- Arterial stiffness increases with deteriorating glucose tolerance status: the Hoorn Study
- Neurodegenerative diseases of the retina and potential for protection and recovery
- New drugs, procedures, and devices for hypertension
- Location of arterial stiffening differs in those with impaired fasting glucose versus diabetes: implications for left ventricular hypertrophy from the Multi-Ethnic Study of …
- Mechanisms of arterial remodeling: lessons from genetic diseases
- The accumulation of the glycoxidation product Nε-carboxymethyllysine in Cardiac Tissues with age, diabetes mellitus and coronary heart disease
- The effects of antihypertensive drugs on arterial stiffness
- Diabetic neuropathy is closely associated with arterial stiffening and thickness in type 2 diabetes
- Targeted reduction of advanced glycation improves renal function in obesity
- To AGE or not to age. The effect of physical activity and advanced glycation end-products (AGEs) on the vasculature in older individuals
- Characteristics, formation, and pathophysiology of glucosepane: a major protein cross-link
- Advanced glycation end‐products induce skeletal muscle atrophy and dysfunction in diabetic mice via a RAGE‐mediated, AMPK‐down‐regulated, Akt pathway
- Molecular mechanisms of diabetic cardiomyopathy
- Glycation: Implication in perceived age and dermatology
- Type-I Angiotensin II Receptor Blockade Reduces Uremia-induced Deterioration of Bone Material
- (−)-Epicatechin Ameliorates Cardiac Fibrosis in a Female Rat Model of Pre-Heart Failure with Preserved Ejection Fraction
- Advanced glycation and advanced lipoxidation: possible role in initiation and progression of diabetic retinopathy
- Protective effect of vanillin on diabetic nephropathy by decreasing advanced glycation end products in rats
- Compounds that combine aldose reductase inhibitory activity and ability to prevent the glycation (glucation and/or fructation) of proteins as putative …
- Alagebrium chloride, a novel AGE cross linkage breaker, inhibits neointimal proliferation after carotid balloon injury in diabetic animal model
- Cardiovascular prevention: relationships between arterial aging and chronic drug treatment
- Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review
- Pathophysiology of diabetic retinopathy
- Heart failure: novel therapeutic approaches
- Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms
- Diabetic cardiomyopathy: do women differ from men?
- Clinic and ambulatory blood pressure in relation to the interaction between plasma advanced glycation end products and sodium dietary intake and renal handling
- Response to “A Short Insight on Two Different Aspects of Arterial Stiffness”; Moving Forward or Backward?
- Renoprotective antioxidant effect of alagebrium in experimental diabetes
- Arterial stiffness and hand osteoarthritis: a novel relationship?
- Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure
- Heart failure with normal ejection fraction
- Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density
- The receptor for advanced glycation endproducts (RAGE) and cardiovascular disease
- Linking RAGE and Nox in diabetic micro-and macrovascular complications
- The next generation of diabetic nephropathy therapies: an update
- Epicatechin breaks preformed glycated serum albumin and reverses the retinal accumulation of advanced glycation end products
- RAGE and cardiovascular disease
- Vieillissement: rôle et contrôle de la glycation
- Therapeutic potential of α-crystallin
- The role of advanced glycation end products in the development of atherosclerosis
- Senescence mediated redox imbalance in cardiac tissue: Antioxidant rejuvenating potential of green tea extract
- Effects of body mass index, plasma glucose and cholesterol levels on isolated systolic hypertension
- Collagen crosslinking: effect on structure, mechanics and fibrosis progression
- Arterial stiffness and arterial wave reflections are associated with systolic and diastolic function in patients with normal ejection fraction
- Influence of lifestyle modification on arterial stiffness and wave reflections
- The kidney in diabetes: dynamic pathways of injury and repair. The Camillo Golgi Lecture 2007
- Aging and ocular tissue stiffness in glaucoma
- Emerging role of advanced glycation-end products (AGEs) in the pathobiology of eye diseases
- The role of advanced glycation end products on sarcoplasmic reticulum calcium handling during diabetic cardiomyopathy
- Tiny molecule, big power: multi-target approach for curcumin in diabetic cardiomyopathy
- Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype
- Microvascular degenerative complications are associated with increased aortic stiffness in type 2 diabetic patients
- Arterial stiffness in renal patients: an update
- Structural proteins and arterial ageing
- The role of AGEs in cardiovascular disease
- Agents that block advanced glycation end product (AGE)-RAGE (receptor for AGEs)-oxidative stress system: a novel therapeutic strategy for diabetic vascular …
- Pharmacologic approaches against advanced glycation end products (AGEs) in diabetic cardiovascular disease
- Vascular compliance in hypertension: therapeutic implications
- Mechanistic targeting of advanced glycation end-products in age-related diseases
- Advanced glycation end products (AGEs), receptor for AGEs, diabetes, and bone: review of the literature
- Therapeutic interventions against accumulation of advanced glycation end products (AGEs)
- Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness
- Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and …
- Emerging drugs for acute and chronic heart failure: current and future developments
- Skin autofluorescence corresponds to microvascular reactivity in diabetes mellitus
- Mutational Studies of the Receptor for Advanced Glycation End Products (RAGE) Inhibition
- Pharmacological evaluation of novel alagebrium analogs as methylglyoxal scavengers in vitro in cardiac myocytes and in vivo in SD rats
- Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans
- Emerging concepts in cardiac matrix biology
- Model studies of advanced glycation end product modification of heterograft biomaterials: The effects of in vitro glucose, glyoxal, and serum albumin on collagen …
- Novel therapeutic targets for diabetic nephropathy
- Glycative stress and anti-aging: 14. Regulation of Glycative stress. 2. Inhibition of the AGE production and accumulation
- Cytotoxicity of advanced glycation endproducts in human micro-and astroglial cell lines depends on the degree of protein glycation
- Alagebrium (ALT-711) improves the anti-hypertensive efficacy of nifedipine in diabetic-hypertensive rats
- Large elastic artery stiffness with aging: novel translational mechanisms and interventions
- Research Article Targeting AGEs Signaling Ameliorates Central Nervous System Diabetic Complications in Rats
- A comparison of dicarbonyl stress and advanced glycation endproducts in lifelong endurance athletes vs. sedentary controls
- Advanced glycation end-products as a potential target for treatment of cardiovascular disease
- ASSOCIATION FOR ACADEMIC SURGERY AND SOCIETY OF UNIVERSITY SURGEONS—ABSTRACTS 260
- Cardiac fibrosis and aging
- Metabolic parameters associated with arterial stiffness in older adults with Type 2 diabetes: the Edinburgh Type 2 diabetes study
- Advanced glycation end products and cardiovascular disease
- In vitro and in vivo antiglycation effects of connarus ruber extract
- Arterial stiffness in predialysis patients with uremia
- ADVANCED GLYCATED END PRODUCTS: A REVIEW
- Longitudinal changes in vascular risk markers and mortality rates among a Latino population with hypertension
- The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease
- Molecular mechanisms associated with diabetic endothelial–erectile dysfunction
- Advanced glycation end product (AGE) accumulation in the skin is associated with depression: the Maastricht study
- Functional and Hemodynam ic Cardiac Determinants of Exercise Capacity in Patients with Systolic Heart Failure
- Advanced glycation end-products in cardiac and renal failure
- Arterial stiffness and stroke: de-stiffening strategy, a therapeutic target for stroke
- Agents in development for the treatment of diabetic nephropathy
- The AGE–RAGE pathway and its relation to cardiovascular disease in patients with chronic kidney disease
- Clinical applications of arterial stiffness: therapeutics and pharmacology
- Future treatment of hypertension: shifting the focus from blood pressure lowering to arterial stiffness modulation?
- Of mice and men: models and mechanisms of diabetic cardiomyopathy
- What are new avenues for renal protection, in addition to RAAS inhibition?
- Medical treatment of Marfan syndrome: a time for change
- Therapeutic modification of arterial stiffness: An update and comprehensive review
- The possible role of advanced glycation endproducts (AGEs) in experimentally-induced ischemic brain damage.
- Age-related intimal stiffening enhances endothelial permeability and leukocyte transmigration
- Slowing arterial aging: how far have we progressed?
- Obesity and vascular compliance
- Arterial stiffness, vascular calcification and bone metabolism in chronic kidney disease
- Skin autofluorescence is increased in systemic lupus erythematosus but is not reflected by elevated plasma levels of advanced glycation endproducts
- Intraoperative sRAGE-Kinetik: Ein neuer altersbezogener Outcome-Prädiktor der kardialen Chirurgie
- Alpha-dicarbonyl stress: implications for obesity and type 2 diabetes?
- Central arterial aging and the epidemic of systolic hypertension and atherosclerosis
- Advanced glycation end-products, measured as skin autofluorescence, associate with vascular stiffness in diabetic, pre-diabetic and normoglycemic …
- Ageing and vascular ageing
- Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
- The bencfit-to-risk ratio of common treatments in PCOS: effect of oral contraceptives versus metformin on atherogenic markers
- Oxidative stress and diabetic retinopathy: Molecular mechanisms, pathogenetic role and therapeutic implications
- RAGE in the pathophysiology of skeletal muscle
- Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin‐treated, apolipoprotein E‐deficient mice
- Corneal stiffness and collagen cross-linking proteins in glaucoma: Potential for novel therapeutic strategy
- Why don’t fistulas mature?
- New insights into the causes of heart failure
- Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications
- 5. Crucial involvement of advanced glycation end-products in experimental diabetes-associated arterial elastocalcinosis.
- The future of aging therapies
- Soluble receptor for advanced glycation end products and increased aortic stiffness in the general population
- Influence of RAGE Signaling on Cellular Communication in Diabetes-Mediated Vascular Calcification
- Current concepts in the management of diabetic nephropathy
- Prognostic impact of aortic stiffness in high-risk type 2 diabetic patients: the Rio de Janeiro Type 2 Diabetes Cohort Study
- Role of advanced glycation end products in cardiovascular disease
- Diabetic Kidney Disease: From Pathogenesis to Novel Treatment Possibilities
- The metabolic syndrome in elderly individuals is associated with greater muscular, but not elastic arterial stiffness, independent of low-grade inflammation, endothelial …
- Lifelong cyclic mechanical strain promotes large elastic artery stiffening: increased pulse pressure and old age-related organ failure
- Arterial blood pressure and stiffness in hypertension: is arterial structure important?
- Erectile dysfunction in the elderly: epidemiology, etiology and approaches to treatment
- Physical activity and markers of glycation in older individuals: data from a combined cross-sectional and randomized controlled trial (EXAMIN age)
- Challenging but essential targets for genuine anti-ageing drugs
- Ventricular arterial stiffening: integrating the pathophysiology
- Diabetic cardiomyopathy: signaling defects and therapeutic approaches
- Inhibition of NA+/H+ Exchanger 1 Attenuates Renal Dysfunction Induced by Advanced Glycation End Products in Rats
- Blood pressure, large arteries and atherosclerosis
- Elevated serum advanced glycation end products and their circulating receptors are associated with anaemia in older community-dwelling women
- Conundrum of pathogenesis of diabetic cardiomyopathy: role of vascular endothelial dysfunction, reactive oxygen species, and mitochondria
- Vascular Stiffness
- Induction and rescue of skeletal fragility in a high-fat diet mouse model of type 2 diabetes: An in vivo and in vitro approach
- Nutrition, Diet, and Supplements for Peak Physical & Mental Performance
- Measurement of arterial stiffness: a novel tool of risk stratification in hypertension
- Receptor for Advanced Glycation End Product, Organ Crosstalk, and Pathomechanism Targets for Comprehensive Molecular Therapeutics in Diabetic Ischemic Stroke
- Alagebrium and spironolactone ameliorate dietary induced metabolic syndrome in male Wister rats
- Advanced glycation endproducts: a biomarker for age as an outcome predictor after cardiac surgery?
- Lens aging: effects of crystallins
- Secondary metabolites from lichen as potent inhibitors of advanced glycation end products and vasodilative agents
- Point of NO return for nitrergic nerves in diabetes: a new insight into diabetic complications
- Diabetic hyperglycemia promotes primary tumor progression through glycation-induced tumor extracellular matrix stiffening
- The Role of Cortical and Cancellous Bone Quality on Vertebral Fragility
- Alagebrium and Spironolactone Ameliorate Dietary Induced Metabolic Syndrome in Male Wister Rats
- Aging and glycoxidant stress
- Microvascular and lymphatic dysfunction in HFpEF and its associated comorbidities
- Advanced glycation end products and vascular structure and function
- Nondiabetic glucometabolic status and progression of aortic stiffness: the Whitehall II Study
- Uncertainty quantification and sensitivity analysis of an arterial wall mechanics model for evaluation of vascular drug therapies
- Extracellular Matrix Viscoelasticity Drives Liver Cancer Progression in Pre-Cirrhotic NASH
- Below the Radar: Advanced Glycation End Products that Detour “around the side”: Is HbA1c not an accurate enough predictor of long term progression and …
- Accumulation of advanced glycation end products and chronic complications in ESRD treated by dialysis
- Drug discovery for heart failure: a new era or the end of the pipeline?
- Alterations in myofilament calcium sensitivity and calcium regulation in type 2 diabetic rat heart
- Using myocardial imaging to identify and manage subclinical heart disease in diabetes mellitus and obesity
- Future Therapies in Diastolic Heart Failure
- Avenues for post-translational protein modification prevention and therapy
- Chemical Approaches to Modulate Biological Processes: Unique Activity of N-Phenacylthiazolium Compounds, Bacterial Cell Wall Engineering and Other …
- Therapeutic agents targeting at AGE-RAGE axis for the treatment of diabetes and cardiovascular disease: a review of clinical evidence
- Zagazig University Medical Journa l
- Different impact of hemodialysis vintage on cause-specific mortality in long-term hemodialysis patients
- Advanced glycation end products: sparking the development of diabetic vascular injury
- Deterioration of Glutaraldehyde crosslinked Heterograft Biomaterials due to Advanced Glycation End Product Formation and Serum Albumin Infiltration
- Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation …
- Relation of aortic distensibility determined by magnetic resonance imaging in patients≥ 60 years of age to systolic heart failure and exercise capacity
- Arterial compliance in the elderly: its effect on blood pressure measurement and cardiovascular outcomes
- Cardiac Fibrosis and Aging
- Large arteries and the kidney
- Hypertension, diabetes type II, and their association: role of arterial stiffness
- Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
- The diabetic cardiomyopathy: the contributing pathophysiological mechanisms
- Methylglyoxal-induced increase in peroxynitrite and inflammation related to diabetes
- Annual update 2004/2005-Treatment of cardiovascular disorders
- Extracellular matrix changes and vascular smooth muscle signaling
- Mechanical factors in arterial aging: a clinical perspective
- Novel therapies for diabetic kidney disease
- Advanced glycation end-products: implications for diabetic and non-diabetic nephropathies
- Novel therapeutic strategies for reducing arterial stiffness
- Heart failure with preserved ejection fraction: an ongoing enigma
- AGE–RAGE stress, stressors, and antistressors in health and disease
- 5 Diabetes and Advanced
- Decreasing arterial aging by controlling blood pressure levels and hypertension: a step forward
- Pacing and Diastolic Heart Failure
- Role of advanced glycation end products (AGEs) and its receptor (RAGE)-mediated diabetic vascular complications
- Free radicals in aging: causal complexity and its biomedical implications
- Cardiovascular Complications in Renal Failure: Implications of Advanced Glycation End Products and Their Receptor RAGE
- RAGE signaling in inflammation and arterial aging
- Effect of Nebivolol and Lifestyle Modification on Large Artery Stiffness in Middle-Aged and Older Hypertensive Adults
- Receptor for advanced glycation end products and the cardiovascular complications of diabetes and beyond: lessons from AGEing
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