Fear extinction is a process in which a learned fear response is reduced or eliminated through repeated exposure to the fear-inducing stimulus in the absence of […]

insulin & aging Reduced Circulating Insulin Enhances Insulin Sensitivity and Extends Lifespan The causal relationships between insulin levels, insulin resistance, and longevity are not fully elucidated. […]

mTor‐dependent stimulation of the association of eIF4G and eIF3 by insulin insulin signalling to mTor mediated by the Akt/PKB substrate PRAS40 The role of mammalian target […]

Excitotoxicity is a process where nerve cells are damaged and killed by excessive stimulation from neurotransmitters, particularly glutamate, leading to an influx of calcium ions into […]

The relationship between polyamines, NMDA, and depression in suicide completers. – **Polyamines and Depression in Suicide Completers:**Spermidine has been associated with suicide completers. Studies examining gene […]

skin aging skin aging skin aging Fifty years of skin aging Molecular mechanisms of skin aging: state of the art Retinoids in the treatment of skin […]

Evaluation of Anti-wrinkle effects of a novel cosmetic containing niacinamide Anti-wrinkle and anti-Inflammatory effects of active garlic components and the inhibition of MMPs via NF-κB signaling […]

anti-aging effect of astragalosides and its mechanism of action. aging: The Reality: “anti-aging” Is an Oxymoron The war on “anti-aging medicine” Role of antioxidants in the […]

The biology of Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling-protein homologues Mitochondrial Uncoupling proteins—what is their physiological role? Superoxide activates Mitochondrial Uncoupling proteins The Mitochondrial Uncoupling proteins […]