ASCENDANCE (Pain Annihilator & Anti-Inflammatory)

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Introducing

ASCENDANCE

Pain Annihilator

Non-Opioid

Anti-Inflammatory

Analgesic Powerhouse


200:1 Concentration

If you are living with supplements for arthritis pain needs that conventional medicine has failed to meet, or searching for a genuine best anti-inflammatory supplement built from the world’s most potent botanical analgesic compounds, ASCENDANCE from Interstellar Blends is the answer. This is not a standard pain relief product. It is a 200:1 concentrated Ascendance herbal formula containing over 100 research-backed botanicals, each selected for its documented capacity to reduce inflammation naturally, block pain signalling pathways, and modulate the cytokine cascades at the root of chronic suffering.

As a pain management supplement and anti-inflammatory supplement, ASCENDANCE targets the biological mechanisms of pain, not just the sensation. For anyone seeking natural pain relief remedies that address cytokine-driven inflammation, nociceptive signalling, and systemic inflammatory load simultaneously, this formula is the most comprehensive pain-relief formula ever assembled from plant-based sources.

Chronic pain is one of the most debilitating conditions in modern medicine, affecting over 50 million adults. Whether driven by arthritis, autoimmune conditions, neuropathy, or musculoskeletal injury, its root is almost always inflammatory. ASCENDANCE is engineered as a supplement for chronic inflammation solution that attacks this root directly, making it equally relevant as a joint pain relief supplement, a pain relief supplement for post-exercise recovery, and a dedicated supplement for chronic pain formula for long-term sufferers.

ASCENDANCE is also the premier dry fasting recovery supplement for those on intensive fasting protocols. Dry fasting and extended fasting accelerate autophagy and cellular repair, but they can also intensify inflammatory flare-ups during refeeding or recovery windows. 

ASCENDANCE provides pain & inflammation relief after fasting by delivering concentrated botanical anti-inflammatory support precisely when the body’s repair processes are most active. It also functions as the best supplements for sciatica pain for fasting practitioners dealing with nerve-related inflammation and pairs seamlessly with other supplements to support fasting protocols.

The Science Behind ASCENDANCE

CYTOKINES & THEIR ROLE IN InFLAMMATION, PAIN & AGING

What are cytokines?

Cytokines are small secreted proteins that regulate communication between cells. They include lymphokines, monokines, chemokines, and interleukins, and they are the primary drivers of both acute and chronic inflammation. Critically, there is significant evidence that certain pro-inflammatory cytokines are involved not only in initiating pain but also in making it persist. This cytokine inflammation supplement targets those cytokine pathways directly, suppressing inflammatory signaling that transforms temporary pain into a chronic, life-limiting condition.


ANTI-INflammatory EFFECTS OF FLAVONOIDS & polyphenols

Flavonoids and polyphenols found throughout the botanical kingdom are among the most studied natural compounds for inflammation suppression. Scientific evidence shows that flavonoids’ anti-inflammatory benefits include the inhibition of regulatory enzymes and transcription factors that control inflammatory mediators, such as COX-2 and NF-kB, which are crucial in the inflammatory response. 

ASCENDANCE is a complete formula made from over 100 plant extracts that help reduce inflammation, provide pain relief, and offer antioxidant protection, which can lessen tissue damage, decrease scarring, and help stop inflammatory diseases from developing.


Inflammaging

Inflammaging refers to the chronic, low-grade inflammation that characterizes aging. It is macrophage-centered, affects multiple tissues and organs, including the gut microbiota, and is driven by the accumulation of cellular debris that activates the innate immune system. As an anti-aging/inflammation reduction formula, ASCENDANCE targets this inflammaging process, supporting autophagy, mitophagy, and the anti-inflammatory signaling pathways that decline with age. For users on keto or fasting protocols, this feature makes it one of the most strategically valuable keto/fasting & inflammation supplements available.


non-Opioid Analgesics

Non-opioid analgesics are used to treat mild, moderate, and severe acute and chronic pain without the dependency risks of opioid medications. Botanical non-opioid compounds avoid the gastric damage of NSAIDs and the physical dependence of opioids with long-term use. ASCENDANCE is built entirely on pain relief without opioids, delivering non-opioid pain relief through natural analgesic ingredients validated in peer-reviewed research.


What ASCENDANCE Addresses

  1. Arthritis & Joint Pain Support: Helps ease joint pain and stiffness by targeting key inflammatory pathways linked with arthritis and joint degeneration, which can improve mobility and enhance quality of life for those affected by these conditions, particularly by reducing swelling and discomfort during daily activities.
  2. Chronic Inflammation Relief: Provides broad anti-inflammatory support to help calm systemic inflammation and support overall body balance.
  3. Fibromyalgia & Widespread Pain: Supports relief from widespread pain by addressing neuroinflammation and sensitivity linked with fibromyalgia.
  4. Back Pain & Sciatica Support: Helps reduce nerve-related inflammation associated with back pain and sciatica for better mobility and comfort.
  5. Muscle Pain & Recovery: Supports muscle recovery, reduces soreness, and helps the body recover faster after intense activity or physical stress.
  6. Autoimmune Support: Helps balance immune responses and calm inflammatory triggers often linked with autoimmune conditions.

Ingredients Science-Backed Botanical Anti-Inflammatory Compounds

Every ingredient in this Ascendance anti-inflammatory formula has been selected for its documented analgesic, anti-inflammatory, or neuroprotective activity. Combined at a 200:1 concentration, this is the world’s most potent plant-based pain relief and plant-based inflammation relief formula.

Aconitum carmichaelii Debx. root

Diterpenoid alkaloid extract that attenuates chronic neuropathic pain by activating ERK/CREB microglial signalling and stimulating dynorphin A production.

Aconitum kusnezoffii Reichb. leaves

Traditional Chinese analgesic shown to effectively reduce severe diabetic peripheral neuropathic pain through combined nerve-repair and analgesic mechanisms.


Acorus calamus 

Neuroprotective plant extract that attenuates chronic neuropathic pain through anti-oxidative, anti-inflammatory, and calcium-inhibitory actions in sciatic nerve injury models.


Aloevera Barbedensis

Leaf extract with significant dose-dependent anti-inflammatory and analgesic activity, reducing oedema and thermal pain response in validated animal models.


Alpinia officinarum Hance root extract

Galangal root with potent anti-inflammatory flavonoids that inhibit COX-2 and pro-inflammatory cytokine production, providing natural pain relief.


Alternanthera brasiliana aerial parts

Brazilian herb whose aerial parts exhibit significant anti-inflammatory and analgesic activity through inhibition of inflammatory mediators and pain pathways.


Anacardium occidentalis leaf 

Cashew leaf extract with anti-inflammatory and analgesic properties that inhibit carrageenan-induced oedema and reduce pain sensitivity effectively.


Andrographis Peniculata

Potent anti-inflammatory herb delivering Andrographis paniculata pain relief by blocking NF-κB signalling, reducing cytokines, and suppressing inflammatory gene expression.


Angelica dahurica root 

Chinese angelica root with coumarin-based compounds that exhibit anti-inflammatory and analgesic activity by inhibiting prostaglandin synthesis and reducing pain signalling.


Angelica pubescens root 

Osthole-rich root extract with documented analgesic and anti-rheumatic properties, traditionally used for joint pain, arthritis, and cold-induced pain conditions.


Antrodia camphorata 

Rare Taiwanese medicinal fungus with potent anti-inflammatory triterpenoids that suppress pro-inflammatory cytokines and reduce inflammatory pain signalling.


Aquilaria sinensis

Agarwood extract containing sesquiterpenes and chromones with documented anti-nociceptive and anti-inflammatory activity through opioid and serotonin receptor modulation.


Ardisia gigantifolia Stapf 

Tropical herb with anti-inflammatory saponins that reduce carrageenan-induced swelling and demonstrate analgesic activity in thermal and chemical pain models.


Artemisia absinthium

Wormwood with absinthin and artabsin compounds that inhibit NF-κB-driven inflammation, providing anti-inflammatory and analgesic relief from chronic pain.


Artemisia herba alba

White wormwood extract with flavonoids and essential oils that suppress cyclooxygenase activity, reducing inflammatory pain and systemic cytokine levels.


AsariRadix Et Rhizoma 

Chinese wild ginger root with analgesic methyleugenol and higenamine compounds that block peripheral pain receptors and reduce neuropathic pain.


Asarum sieboldii Miq.

Japanese wild ginger with documented local anaesthetic and analgesic properties through sodium channel blockade, reducing acute and chronic pain signals.


Astragali radix

Astragalus root extract that reduces inflammatory cytokines, enhances immune regulation, and supports tissue repair in chronic inflammatory and autoimmune conditions.


Aucklandia lappa Decne. root extract

Costus root with sesquiterpene lactones that potently inhibit NF-κB, suppressing pro-inflammatory mediators and providing relief from chronic inflammatory pain.


Averrhoa carambola L.

Starfruit extract with quercetin and kaempferol compounds that inhibit cyclooxygenase and lipoxygenase enzymes, reducing inflammation and associated pain signals.


Borassus flabellifer flowers

Palmyra palm flower extract with anti-inflammatory and analgesic flavonoids that suppress prostaglandin synthesis and reduce pain-related inflammatory responses.


Boswellia carterli 

Frankincense resin extract with boswellic acids that specifically inhibit 5-LOX, reducing leukotriene production and providing powerful joint and chronic pain relief.


Boswellia serrata resin 

Clinically validated frankincense resin with AKBA compounds that reduce cartilage-degrading enzymes, supporting osteoarthritis and rheumatoid arthritis pain management.


Caesalpinia sappan L. 

Sappanwood with brazilin and protosappanin compounds that inhibit nitric oxide production and suppress inflammatory cytokines including IL-6 and TNF-alpha.


Callicarpa formosana Rolfe 

Taiwanese beauty-berry with phenylethanoid glycosides that demonstrate significant anti-inflammatory activity by suppressing inflammatory enzyme and cytokine production.


Campsis grandiflora

Trumpet vine flower extract with caffeic acid and flavonoids that exhibit anti-inflammatory and analgesic properties in validated experimental pain models.


capsaicin

Chili compound that depletes substance P from nociceptive neurons, providing profound and sustained pain relief through TRPV1 receptor desensitisation.


Cardiospermum halicacabum L. 


Balloon vine extract with anti-inflammatory steroidal compounds used traditionally for arthritis and joint pain, validated for COX inhibition and cytokine suppression.


Carthamus tinctorius L. flower 


Safflower with carthamin and flavonoids that improve blood circulation, reduce inflammatory pain, and protect against oxidative stress in inflamed tissues.


Chelidonium majus 

Greater celandine with alkaloids including chelidonine that exhibit analgesic and spasmolytic activity by modulating pain receptor pathways and smooth muscle tension.


Cimifugin (Saposhnikovia divaricata)

Root-derived chromone compound with potent anti-inflammatory and analgesic activity, suppressing NF-κB and reducing inflammatory cytokine cascades in chronic pain.


Cinnamomum cassia peel 

Cinnamon bark with cinnamaldehyde that inhibits NF-κB and MAPK inflammatory signalling, reducing joint inflammation and providing natural analgesic benefits.


Cinnamon Zeylanicum

Ceylon cinnamon with eugenol and coumarin compounds that suppress cyclooxygenase-mediated inflammation and provide antioxidant protection in inflammatory tissues.


Cissampelos pareira

Velvet leaf with alkaloids including cissampeline that exhibit analgesic and anti-inflammatory properties through central and peripheral pain pathway modulation.


Cissus quadrangularis

Climbing cactus with anabolic steroids and flavonoids that accelerate bone and joint repair, reduce inflammation, and support chronic joint pain relief.


Clematis chinensis Osbeck

Chinese clematis with saponins that suppress inflammatory cytokines, inhibit prostaglandin synthesis, and provide analgesic relief from arthritis and joint pain.


collybolide (Collybia maculata)

Mushroom-derived sesquiterpene with potent kappa-opioid receptor agonist activity that produces powerful analgesic effects without opioid addiction potential.


Conolidine (Tabernaemontana divaricate)

Rare indole alkaloid from crepe jasmine bark that activates novel pain-relief pathways independent of opioid receptors, providing potent non-opioid analgesia.


Conus striatus venom

Cone snail venom containing conotoxins that block specific sodium and calcium channels responsible for neuropathic pain transmission at the source.


Corydalis yanhusuo

Traditional Chinese analgesic herb with tetrahydropalmatine and dehydrocorybulbine that block dopamine receptors to produce broad-spectrum analgesic and anti-inflammatory effects.


Curcuma alismatifolia

Chiang Rai tulip extract with anti-inflammatory curcuminoids and sesquiterpenoids that reduce inflammatory cytokines and support chronic pain management naturally.


Curcuma longaL root 

Turmeric root with curcuminoids that inhibit COX-2, NF-κB, and TNF-alpha, providing comprehensive anti-inflammatory and analgesic support for chronic pain conditions.


Curcumae Radix

Zedoary root with curcumin and zedoarone compounds that exhibit potent anti-inflammatory, analgesic, and antioxidant activity across multiple inflammatory pathways.


curcumin

Isolated turmeric polyphenol with the most clinically studied natural anti-inflammatory profile, inhibiting over 60 molecular targets involved in inflammation and pain.

Daemonorops draco 

Dragon’s blood resin with flavonoids and phenolic compounds that reduce acute and chronic inflammation by suppressing prostaglandin and inflammatory cytokine production.


Dalbergia sissoo

Rosewood with isoflavonoids and flavonoids that exhibit anti-inflammatory and analgesic properties by inhibiting prostaglandin synthesis and reducing oxidative tissue damage


Dalbergiae Odoriferae Lignum 

Fragrant rosewood heartwood extract with phenolic compounds that suppress NF-κB-mediated inflammation and provide analgesic relief in inflammatory pain models.


Daphne retusa

Himalayan daphne with daphnoretin and other coumarins that inhibit pro-inflammatory mediators and provide documented analgesic and anti-inflammatory activity.


Desmodium triflorum 

Three-flower beggarweed with alkaloids and flavonoids that demonstrate significant anti-inflammatory and analgesic activity through prostaglandin inhibition pathways.


Drymaria cordata 

Tropical herb with saponins and flavonoids that exhibit anti-nociceptive and anti-inflammatory properties by modulating central and peripheral pain receptors.


Elettaria cardamonuum

Cardamom with terpene compounds that suppress inflammatory enzymes, reduce oxidative stress, and provide mild but consistent analgesic and anti-inflammatory support.


epibatidine

Alkaloid from poison dart frogs with extraordinary potency at nicotinic acetylcholine receptors, producing analgesic effects 200x stronger than morphine non-opioidally.


Erythrina variegata peel 

Coral tree bark extract with erythraline alkaloids that exhibit muscle-relaxant and analgesic properties, reducing pain from muscle spasm and nerve compression.


Eugenia supra-axillaris leaf 

Tropical Eugenia leaf extract with anti-inflammatory and analgesic flavonoids that inhibit carrageenan-induced inflammation and reduce both acute and chronic pain.


Evodia rutaecarpa fruit 

Wu Zhu Yu fruit with evodiamine and rutaecarpine that inhibit TRPV1, reduce neuroinflammation, and provide potent analgesic effects in neuropathic pain.


Ferula assa-foetida 

Asafoetida resin with ferulic acid and farnesiferol compounds that inhibit NF-κB and cyclooxygenase, providing anti-inflammatory and analgesic relief.


Ficus palmata fruit

Wild Himalayan fig fruit extract with anti-inflammatory compounds that reduce inflammatory mediator production and support natural pain relief in joint and muscle pain.

Flemingia strobilifera

Shatapushpa herb with flavonoids and isoflavones that exhibit anti-inflammatory activity by modulating arachidonic acid metabolism and cytokine signalling pathways.


Fragaria vesca

Wild strawberry with ellagic acid and quercetin that reduce inflammatory cytokines, inhibit COX enzymes, and provide antioxidant-driven anti-inflammatory support.


Fumaria capreolata


Ramping fumitory with alkaloids including fumariline that demonstrate analgesic and antispasmodic properties, reducing pain associated with smooth muscle tension.


Gentiana kurroo root 


Himalayan gentian with xanthone compounds that exhibit potent anti-inflammatory activity by inhibiting NF-κB and reducing pro-inflammatory cytokine expression.

Harpagophytum (DEVIL’s CLAW)


Devil’s claw root with harpagoside compounds clinically validated for reducing arthritic joint pain, lower back pain, and chronic musculoskeletal inflammation.

Holarrhena antidysenterica leaves

Kutaja leaves with steroidal alkaloids that reduce inflammation and pain through multiple mechanisms including cyclooxygenase inhibition and cytokine modulation.


Hydrocotyle batrachium 

Frogbit pennywort extract with triterpenoids and flavonoids that demonstrate anti-inflammatory and analgesic properties in models of acute and chronic pain.


Hydrocotyle umbellata 


Marsh pennywort with asiaticoside and madecassoside that accelerate wound healing, reduce inflammation, and support nerve repair in neuropathic pain conditions.

hyperforin and hypericin (St. JoHn’s Wort))

Bioactive St. John’s Wort compounds that inhibit serotonin, dopamine, and norepinephrine reuptake, producing analgesic and anti-neuropathic pain effects.


Illicium verum fruit 

Star anise with trans-anethole and shikimic acid that inhibit inflammatory mediators, reduce oxidative stress, and provide anti-nociceptive and analgesic support.


Impatiens balsamina

Garden balsam with lawsone and flavonoids that exhibit anti-inflammatory and analgesic properties by suppressing cyclooxygenase and lipoxygenase enzyme activity.


Imperata cylindrica root 

Cogon grass root with cylindrene and flavonoids that reduce fever, inflammation, and pain through anti-inflammatory enzyme inhibition and immune modulation.


Jasminum amplexicaule

Climbing jasmine with oleuropein and flavonoids that exhibit significant anti-inflammatory and analgesic activity in validated experimental inflammation models.


Juglans regia leaf (WALNUT)

Walnut leaf with juglone and ellagic acid that reduce inflammatory cytokines, inhibit NF-κB activity, and provide antioxidant-driven anti-inflammatory relief.


Kadsura interior A .C. Smith 

Schisandroid vine with lignans including kadsuranin that exhibit potent anti-inflammatory and analgesic properties by blocking pain-mediating inflammatory enzymes.


Lactuca scariola (prickly lettuce)

Wild lettuce with lactucin and lactucopicrin that bind opioid receptors, producing sedative and analgesic effects comparable to low-dose opioid analgesia.


Lamiophlomis rotata 

Tibetan herb with iridoid glycosides that exhibit anti-nociceptive and anti-inflammatory activity, traditionally used for arthritis and pain in high-altitude medicine.


Landolphia owariensis

West African rubber vine root with triterpenoids that demonstrate significant analgesic and anti-inflammatory properties in models of thermal and chemical pain.


Lecaniodiscus cupanioides root 

African tropical root with saponins and flavonoids that demonstrate significant anti-nociceptive activity through peripheral pain pathway modulation and cytokine suppression.


Leonurus japonicus

Chinese motherwort with alkaloids and flavonoids that exhibit analgesic and anti-inflammatory properties through modulation of pain receptor signalling.


Ligularia fischeri

Korean goldenrod with pyrrolizidine alkaloids and flavonoids that suppress inflammatory enzyme activity and reduce inflammatory pain in musculoskeletal conditions.


Ligusticum chuanxiong

Sichuan lovage with tetramethylpyrazine that improves microcirculation, reduces neuroinflammation, and provides potent analgesic support for headache and joint pain.


Ligusticum porteri (osha root)

Mountain lovage root with phthalides and ferulic acid that act as natural anti-inflammatory and analgesic compounds, particularly effective for respiratory and musculoskeletal pain.


Litsea monopetala leaves 

Tropical Litsea leaves with alkaloids and flavonoids that exhibit potent anti-inflammatory and analgesic activity through COX inhibition and cytokine suppression.


Mallotus repandus stem

Climbing mallotus with triterpenoids and phenolic compounds that exhibit anti-inflammatory and analgesic activity by modulating prostaglandin and leukotriene pathways.


mangiferin

Mango-derived xanthone compound that inhibits NF-κB, reduces TNF-alpha, and provides comprehensive anti-inflammatory and analgesic activity across multiple pain pathways.


Menispermum dauricum root 

Asiatic moonseed root with dauricine alkaloids that exhibit analgesic and anti-inflammatory properties through calcium channel blockade and cytokine inhibition.


Mentha spicata (spearmint)

Spearmint with carvone and limonene that exhibit anti-inflammatory and mild analgesic properties, reducing prostaglandin-driven pain and inflammatory enzyme activity.


Mimosa pudica (sensitive plant)

Mimosa root extract with mimosin and flavonoids that demonstrate central analgesic activity and anti-inflammatory properties in validated pain models.


mitragynine (kratom)

Indole alkaloid from Mitragyna speciosa that activates mu-opioid receptors and adrenergic pathways, producing potent analgesic effects for chronic pain management


Morinda Citrifolia (noni)

Noni fruit with damnacanthal and iridoids that inhibit COX-2, reduce inflammatory cytokines, and provide documented analgesic and anti-inflammatory support.


Moringa oleifera 

Miracle tree with isothiocyanates and quercetin that inhibit NF-κB and COX-2, reducing systemic inflammation and supporting chronic pain management naturally.


Nardostachys chinensis root

Himalayan spikenard root with jatamansone and nardin compounds that exhibit potent anti-inflammatory and analgesic activity through cytokine and enzyme inhibition.


Nigella sativa seeds

Black seed with thymoquinone that inhibits cyclooxygenase and 5-lipoxygenase, providing powerful anti-inflammatory and analgesic effects documented in over 200 studies.


Nyctanthes arbor-tristis stem bark

Night jasmine bark with glycosides and alkaloids that exhibit anti-arthritic, anti-inflammatory, and analgesic properties validated in carrageenan inflammation models.


Ocimum basilicum (basil)

Sweet basil with eugenol and rosmarinic acid that inhibit COX enzymes and reduce prostaglandin production, providing natural anti-inflammatory and analgesic support.


Onosma bracteatum

Gaozaban herb with pyrrolizidine alkaloids and phenolic acids that exhibit anti-inflammatory and analgesic properties through prostaglandin pathway inhibition.


Opuntia dillenii (prickly pear)

Cactus fruit with betacyanins and flavonoids that reduce oxidative stress, inhibit inflammatory cytokines, and support anti-inflammatory pain management naturally.


Oroxylum indicum seed 

Indian trumpet tree seed with baicalein and chrysin that inhibit lipoxygenase and cyclooxygenase, providing potent anti-inflammatory and analgesic relief.


Paederia scandens

Skunkvine with alkaloids and iridoids that exhibit anti-inflammatory and analgesic properties, used traditionally for rheumatic pain and joint inflammation.


Paeonia lactiflora root (white peony)

Peony root with paeoniflorin that modulates immune responses, inhibits inflammatory cytokines, and provides documented analgesic effects in arthritis pain models.


Papaver libanoticum 

Lebanese poppy with flavonoid alkaloids that exhibit analgesic properties through mild opioid pathway modulation without classical opioid side effect profiles.


passion fruit peel

Passiflora peel with piceatannol and flavonoids that reduce inflammation, inhibit cyclooxygenase activity, and provide mild analgesic and anti-inflammatory support.


Perilla frutescens

Perilla leaf with rosmarinic acid and luteolin that potently inhibit COX-2 and 5-LOX, providing comprehensive anti-inflammatory and analgesic benefits.


Phoenix sylvestris (wild date palm)

Date palm with polyphenols and sterols that exhibit anti-inflammatory and analgesic properties, reducing prostaglandin-driven pain and inflammatory oedema.


Phyllanthus amarus

Stone breaker herb with phyllanthin and hypophyllanthin that exhibit analgesic and anti-inflammatory activity by suppressing prostaglandin synthesis pathways.


Phyllanthus corcovadensis

Brazilian Phyllanthus with lignans that exhibit anti-nociceptive and anti-inflammatory properties through both central and peripheral pain pathway modulation.

Phyllanthus niruri

Chanca piedra with ellagic acid and rutin that inhibit inflammatory enzymes, reduce cytokine production, and provide natural pain and inflammation relief.


Phyllanthus tenellus

Slender Phyllanthus with phenolic compounds that exhibit anti-nociceptive and anti-inflammatory activity in experimental models of acute and chronic pain.


Piper betle leaves

Betel vine leaves with eugenol and hydroxychavicol that inhibit COX-2 and lipoxygenase, providing potent anti-inflammatory and analgesic activity.


Piper longum (long pepper)

Long pepper with piperine that enhances bioavailability of other compounds, inhibits NF-κB, and provides direct anti-inflammatory and analgesic contributions.


Pleurotus eous mushroom

Pink oyster mushroom with beta-glucans and phenolic acids that modulate immune cytokine production, reducing inflammatory pain and supporting immune regulation.


Polygala anatolica 

Anatolian milkwort with saponins and flavonoids that exhibit analgesic and anti-inflammatory properties through modulation of pain-mediating enzyme activity.


Polygala jaPonica 

Japanese milkwort with triterpenoid saponins that demonstrate central and peripheral analgesic activity and anti-inflammatory effects in validated pain research.


Polygonum cuspidatum root (japanese knotweed)

Rich resveratrol source that inhibits NF-κB and COX-2, reduces inflammatory cytokines, and provides potent anti-inflammatory and anti-aging analgesic benefits.


Polyphylla Paris Rhizome

Herb Paris with polyphyllin saponins that exhibit potent anti-inflammatory and analgesic properties by suppressing cytokine cascades and inflammatory enzyme activity.


Propolis

Bee-derived resin with caffeic acid phenethyl ester (CAPE) that inhibits NF-κB and COX enzymes, providing documented anti-inflammatory and natural analgesic activity.


Psammosilene tunicoides root 

Himalayan plant root with cyclopeptide alkaloids that exhibit potent anti-nociceptive and anti-inflammatory activity through opioid and NMDA receptor modulation.


Psychotria sarmentosa

Rubiaceae herb with alkaloids that exhibit analgesic and anti-inflammatory properties through suppression of pain-signalling neurotransmitter and cytokine pathways.


Pterocephalus hookeri

Tibetan herb with iridoid glycosides that demonstrate potent anti-inflammatory and analgesic activity, used traditionally for arthritis and rheumatic conditions.


Punica granatum (Flower)

Pomegranate flower with ellagic acid and punicalagin that inhibit NF-κB and COX-2, providing potent anti-inflammatory and antioxidant pain management support.


Pycnogenol (maritime pine bark)

Clinically validated pine bark extract that inhibits COX-1 and COX-2, reduces inflammatory cytokines, and provides documented relief for arthritis and chronic pain.


Qianghuo Shengshi

Traditional Chinese herb formula with volatile oils that exhibit anti-inflammatory and analgesic properties for wind-cold arthralgia and musculoskeletal pain relief.


Resveratrol

Grape-derived polyphenol that inhibits NF-κB, COX enzymes, and inflammatory cytokines, providing potent anti-inflammatory, analgesic, and anti-aging benefits.


Ricinus communis seed (castor)

Castor seed with ricinoleic acid that activates EP3 prostaglandin receptors, providing anti-inflammatory relief through a unique, non-COX-mediated analgesic pathway.


Rosa damascena (damak rose)

Rose extract with geraniol and citronellol that inhibit inflammatory enzymes, reduce oxidative stress, and provide mild analgesic and anti-inflammatory benefits.


rosmarinic acid (rosemary)

Potent phenolic acid that inhibits COX-2, 5-LOX, and complement activation, providing comprehensive plant-based anti-inflammatory and analgesic relief.


Rumex crispus aerial

Yellow dock with anthraquinones and flavonoids that reduce inflammatory cytokine production and provide analgesic support for chronic joint and muscle pain.


Salvia miltiorrhiza root (danshen)

Chinese sage root with tanshinones and salvianolic acid that inhibit inflammatory enzyme activity, reduce cytokines, and support circulation-based pain relief.


Sargassum ilicifolium (brown seaweed)

Marine algae with fucoidan and phlorotannins that inhibit NF-κB, reduce inflammatory cytokines, and provide potent marine-sourced anti-inflammatory and analgesic benefits.


Solanum torvum

Turkeyberry with steroidal alkaloids that exhibit anti-inflammatory and analgesic properties through COX enzyme inhibition and inflammatory pathway suppression.


Solanum tuberosum peel 

Potato peel with chlorogenic acid and glycoalkaloids that exhibit anti-inflammatory and analgesic activity by inhibiting prostaglandin synthesis pathways.


Spatholobus suberectus 

Millettia stem with flavonoids and phenolic acids that improve blood circulation, reduce inflammatory pain, and support joint and musculoskeletal pain management.


Spilanthes acmella (toothache plant)


Toothache plant with spilanthol that exhibits local anaesthetic and anti-inflammatory activity by blocking sodium channels and reducing inflammatory mediator production.


Stauntonia chinensis 

Chinese stauntonvine with saponins and flavonoids that demonstrate analgesic and anti-inflammatory activity through both peripheral and central pain pathway modulation.


Stephania japonica leaf 

Japanese stephania with stepharine and cepharanthine alkaloids that exhibit potent anti-inflammatory and analgesic properties through multiple pain pathway inhibition.


Strychnos nux-vomica (Loganiaceae)

Nux vomica with brucine alkaloid that provides analgesic and anti-inflammatory activity at sub-toxic concentrations through glycine receptor modulation in pain pathways.


Termitomyces albuminosus

Termite mushroom with polysaccharides and ergosterol derivatives that exhibit anti-inflammatory and immune-modulatory properties for systemic inflammation support.


Tetrahydropalmatine

Corydalis-derived alkaloid that blocks dopamine receptors to produce sedative, analgesic, and anti-inflammatory effectsa validated non-opioid pain relief compound.


Thuja Orientalis (oriental arborvitae)

Cedar leaf with quercetin and amentoflavone that inhibit COX enzymes, reduce inflammatory cytokines, and provide antioxidant-driven anti-inflammatory and analgesic support.


Typha angustifolia pollen

Cattail pollen with isorhamnetin and quercetin that exhibit anti-inflammatory and analgesic activity by suppressing prostaglandin and inflammatory cytokine production.


Uncaria gambier

Gambir plant with catechins and rynchophylline that modulate inflammation, reduce cytokine production, and support analgesic activity in chronic inflammatory conditions.


Uncaria tomentosa (cat’s claw)

Amazonian cat’s claw with oxindole alkaloids that modulate immune function, inhibit NF-κB, and provide potent anti-inflammatory relief for arthritis and chronic pain.


Urtica dioica (aerial)

Nettle leaf with lectins and flavonoids that inhibit NF-κB and COX-2, reduce TNF-alpha, and support anti-inflammatory relief for arthritis and muscle pain.


Vaccaria segetalis seed 

Cowherb seed with saponins and flavonoids that promote blood circulation, reduce inflammation, and provide analgesic support for chronic pain conditions.


Veronica peregrina 

Wandering speedwell with iridoids and phenolic compounds that exhibit anti-inflammatory and analgesic properties through prostaglandin pathway suppression.


Vicoa indica

Indian fleabane with sesquiterpene lactones that demonstrate significant anti-inflammatory and analgesic activity by inhibiting NF-κB and cytokine production pathways.


Wilbrandia ebracteata

Brazilian cucurbit with cucurbitacins that exhibit potent anti-inflammatory and analgesic properties through inhibition of cyclooxygenase and lipoxygenase enzymes.


Xanthium sibiricum 

Siberian cocklebur with xanthatin and chlorogenic acid that demonstrate anti-inflammatory and analgesic activity by suppressing prostaglandin and cytokine production.


Xanthium strumarium L.

Common cocklebur with xanthostrumarin that exhibits anti-inflammatory activity by inhibiting NF-κB signalling and reducing pro-inflammatory mediator production pathways.


Zanthoxylum nitidum (Z. nitidum)


Shining prickly ash with nitidine and benzophenanthridine alkaloids that exhibit potent analgesic and anti-inflammatory activity through multiple pain receptor pathways.


Zingiber officinale (ginger)


Ginger root with gingerols and shogaols that inhibit COX and LOX enzymes, reduce inflammatory cytokines, and provide clinically documented analgesic and anti-inflammatory relief.

Who Is ASCENDANCE For?

ASCENDANCE is the most complete herbal pain relief formula and ASCENDANCE pain relief supplement available. It is ideal for:

  • People with arthritis, rheumatoid arthritis, or osteoarthritis are seeking natural remedies for joint pain at a molecular level.
  • Those with fibromyalgia, neuropathy, or sciatica are looking for pain relief for fibromyalgia and natural back pain relief without opioids.
  • Individuals with autoimmune conditions need supplements that address cytokine overproduction, such as omega-3 fatty acids and curcumin, which can help reduce inflammation and improve joint health.
  • Athletes and exercisers are in search of supplements that can alleviate muscle pain and support muscle inflammation.
  • Practitioners of dry fasting require supplements to aid in their recovery and to alleviate pain and inflammation following their fast.
  • Anyone wanting non-opioid pain relief and pain relief without opioidsfull stop.
  • Those on keto protocols seeking keto/fasting & inflammation supplements that address inflammaging and chronic low-grade inflammation.

How to Take ASCENDANCE

Take 2 capsules daily with a glass of water, preferably with a meal to support better absorption and digestive comfort. Consistent daily use allows the botanical compounds to build their supportive effects in the body.

For best results, use ASCENDANCE as part of your regular wellness routine. Many users take it during periods of inflammation, joint discomfort, physical recovery, or when seeking ongoing support for mobility and overall inflammatory balance.

Simple Steps

  • Take 2 capsules once daily
    • Swallow with a full glass of water
    • Best taken with food
    • Use consistently for optimal results

Buy Ascendance Supplement Online: Natural Pain Relief Products

ASCENDANCE is the world’s most concentrated botanical anti-inflammatory compound 

formula. With over 100 research-backed ingredients at 200:1 concentration, it is the most comprehensive Ascendance anti-inflammatory and plant-based supplement ever formulated and the most credible natural pain relief supplement for anyone dealing with chronic, inflammatory, or neuropathic pain.

If you are ready to experience genuine pain management and natural support through botanical science, buy the Ascendance supplement for pain relief online at dryfasting.com today. 

Buy the Ascendance supplement now and take control of your inflammation, your pain, and your quality of life.

This supplement works in synergy with SIRT1 ACTIVATOR and CERAMIDE BLOCKER to provide a comprehensive anti-inflammatory and anti-aging protocol.

Size

25g, 100g

19 reviews for ASCENDANCE (Pain Annihilator & Anti-Inflammatory)

  1. Rated 5 out of 5

    Tammy Bell

    Sciatic nerve pain. So, I’ve been dealing with sciatica pain for about 10 years on the right side of my butt cheek. I had lower back pain, burning down my leg, difficulty moving around in the bed before I would go to sleep. I would do some exercises to try and alleviate the sciatic pain…which only helped for a short time. At one time, I was going to the chiropractor 3 times a week to get adjusted for 3 months straight. I was even considering getting cortisone injections because the pain was so severe. I even did physical therapy a couple times a week…which didn’t help at all! The doctor prescribed anti-inflammation medication that would stop me from having (my) regular bowel movements. Hell, I had to stop that, because I wouldn’t have a BM for like 5 days and would end up taking a laxative. I just realized last night while lying in the bed, that my pain is GONE!!! I don’t know which blend that’s stopping the pain BUT I’m truly thankful that the pain is gone!!! I would wake up in the middle of the night because of the pain and now…NO MORE BACK PAIN!

    Gavin, words couldn’t truly express the thankfulness that I’m feeling being pain free! Thank you so much for all that you and Kristine do!”

  2. Rated 5 out of 5

    Trinity Blackwell

    My whole life I’ve struggled off and on with breathing, inflammation, allergies, digestion, brain fog, pain, energy, and focus. I’ve studied and trained and spent $$$$$. My health would improve and then go downhill again with any stressor. It came to an unsustainable place about a year and a half ago and I had to reboot and change everything. Again. I survived the ordeal and made a lot of progress, but there was still something missing.
    After receiving my 11 blend challenge I started right away, which makes it hard to single out specific blends. After a few days (3 or 4?) the first change I noticed was my ability to handle temperature changes and reduction of inflammation. I went to a hot yoga class, which usually is difficult and makes me feel sick. Instead, it was a breeze, my body was easy to move, and I felt energized and more alive. The next change I noticed was my mood and focus. Suddenly my head felt clear and dealing with teenagers, taxes and work felt straight forward and simple, instead of anxiety provoking and fatiguing. I had more energy to exercise, and I stopped needing to take naps midday. I also completed an 8 day water/electrolyte/blends fast and my first 4 day dry fast. Wow! I have done a lot of water and electrolyte fasting in the past but never like this. I could have kept going, but caution rather than hunger made me stop. I was absolutely not hungry and by day 8 I was maybe a little too enthusiastic and energetic for my family 😅.
    Although it’s hard to differentiate which blends do the most for me I’d say my top 3 are Trinity, Autophagy,, and Thermo.
    Of course, I took all these benefits for granted since it felt so natural and stopped the blends two different times, once for a week, and the second time for a few days. Only to notice my old experiences creeping up on me. No more. I’m a believer. Thank you Gavin for all your research, recommendations, work, and quick response to my questions.“

  3. Rated 5 out of 5

    Joshua

    Hey Gavin, just wanna say man you’ve changed my life with these blends I’ve been taken for about 3 months I wanna say now and wow dude I don’t how u get ahold of these magical elixirs but I had like this weird pinching nag and a little lump near the neck and collar bone and ever since I’ve taken them it has eased the pain. I can just endure a lot and tolerate more bs I thought I couldn’t but anyways u definitely rock! Stay blessed!

  4. Rated 5 out of 5

    Wern

    Listen up!! It took me 3 years to make the buying decision. In all honesty, I was skeptical and unsure of how good a human being can actually feel. For years I’ve been trying different things to try to get rid of afternoon fatigue, brain fog, and irritability. At the beginning of 2022 I started feeling very edgy and more tired than not.

    Something led me back to Gavin. I wrote to him and received a response within minutes; rare to find such fast and direct communication from company owners these days! Especially at the scale at which this man operates.

    I took a combo of Trinity, Nebula, Luteolin, Rewire, Autonomous, and Pine Pollen. Bam! What an introduction to Interstellar Blends. Everything that people has to say about the blends are spot on. The only difference is you only KNOW once you try them. Nobody can tell you have good this stuff is and how good you can feel until you’re on it. I feel happier, more excited, bolder, more confident, more open, and more chilled, all at the same time. AND I started making more money! Coincidence? Nope. Blends!

    The sense of calm and focus you’re able to experience from the start of the day till the end is incredible. I remember writing to Gavin, telling him: “Holy $h*t man. This stuff is on another level. I feel clear-minded, but not high. I don’t know what more to say to you other than Thank You.”

    I have to add that I have tried many nootropics such as modafinil (the most commonly known) which pretty much just put me on a buzz and gave me the jitters. There was some degree of clarity but nothing comes close to Trinity x Autonomous x Nebula. Zero buzz. Zero jitters. Even with high doses of coffee, I do not feel irritable anymore. Since starting 22/2 fasting with blends my body has changed in many ways. The most noticeable is a reduction of lower ab and back fat along with less joint pain and inflammation.

    The entire Interstellar-experience is 5-star! I f$cklng love what Gavin has created. There is no substitute. None. Zero. I am grateful for finding you, brother. I thank you for your service, your time and, your dedication to bringing change to the world.

    To anyone reading this, you CANNOT go wrong! Your life WILL change. Spend $100-$200 to start and I promise you, you will never ever look back.

  5. Rated 5 out of 5

    Lisa A

    I was led to Gavin’s blends a couple of years ago while on a quest to do a successful long term fast. I found that he has the blends to not only suppress cravings but to go to the source and eliminate them. He also not only stands by his products but literally is available what seems to be an unattainable 24×7 when you might be experiencing a purge from your body while using PURGE and having trouble deciphering which bodily portal the elimination process is trying to use.
    When using the blends exactly as directed the results are phenomenal! Even at times when admittingly my taking them in a half-assed approached has alleviated stress, knee injuries, hip pain (to the point I barely can walk and my husband screaming, “you need a new hip”)
    Even while getting COVID (was not taking blends as I should, take the VICTORIOUS daily!) I started fasting and taking blends and the COVID went away along with the dreaded hair loss 3 months later. I have just turned 57 and at my annual physical my doctor said had he not known me he would have thought I was 20 years younger. I definitely attribute my sustained youth to Gavin and his dedication to his quality of blends and clients.

  6. Rated 5 out of 5

    Ken H

    I began the Interstellar Blends journey just over a year ago now. Based on the recommendation of my 30 year old son. He had been using them for several months. To hear him speak of his ability to better focus and his clarity of thought throughout the day was enough to sell me on the products. He suggested an assortment of blends to start and we placed an order.

    Once we received the shipment I had to delay the start due to carpel tunnel surgery on both hands. Pre operative instructions said to stop all supplements a week prior to my procedure. Surgery took place 10/19/21.
    Interstellar journey commenced on 10/20.

    My order consisted of ….Thermo, EKG, ALZ, ACB, VICTORIOUS, SENOLYTIC, TRINITY, SUPERNOVA, PEEL, SPICE, PARASLAYER, HELICO, HYPNOTIC, LUTEOLIN, AND THUNDER.
    I have taken all of these each day for over a year now. Except when traveling.
    I added 7 Sages a while back for the times I travel.

    To say I was amazed at the speed of my recovery from surgery would be an understatement. Being a 65 yr old male who still works in the electrical construction industry my body has gotten pretty beat up over the years. Thanks to Gavins blends I often times feel like I am a 40 yr old again.
    I am still able to hike and bike on a regular basis and after 4 rotator cuff repairs still play golf on a regular basis.

    In a recent order Gavin thought to include a sample of a pain/inflammation neutralizer. I had never seen it on the website. I have been taking it twice a day in black coffee and grapefruit juice. The changes in my left knee and shoulder are quite remarkable. I do hope I can spot it on the menu for my next order.

    Gavin your products are a blessing. I feel I will be a lifelong customer. Thank you Sir.

  7. Rated 5 out of 5

    Patty

    I’ve been taking the blends for over a year. LET ME TELL YOU, these are by far the BEST thing I stumbled upon. I have always been into alternative medicine and am never willing to take what big Pharma is pushing on me. I am a retired Registered Nurse and have pushed back against Pharma my entire career…weird right but my eyes were opened.

    I have suffered with arthritis, pain, low energy but feeling of impending doom, thinning hair, and high blood pressure. Let me tell you….I tried many supplements to try and reverse these symptoms and nothing worked. Again by the Grace of God, I came across Gavin and his life saving blends. What a game changer!!

    Here’s my results. By taking Peel and Spice for Arthritis, I have function back in my wrists and pain is under control. Low Energy and impending doom? GONE with NEBULA and TRINITY…I have never felt so calm and let things pass in my entire life! I use to be high strung and everything effected me. After having what I think was COVID..(never got tested) I started loosing my hair. How disturbing to me. I have been taking the hair blend and is thankfully growing back. Last but not least, EKG has brought my blood pressure into normal range. At every annual physical, my blood pressure was so high sometimes they didn’t want me to leave the clinic. This is a game changer for me. So happy I’m not in the critical zone anymore.

    I could go on and on about the blends. Purge, Glucose Blocker, Anti Adipogenic, Thermo, and Autophagy for loosing weight…OFF THE CHARTS. I lost 10 pounds and have kept it off for over a year.

    This is getting long so just try them….you’ll never go back! Thank You Gavin so much for your life saving and beautiful blends. They are filled with Love.

  8. Rated 5 out of 5

    Ms. Reyes

    I have been an Interstellar customer for over two years. Within that time, I have shared the “magic” of these blends with anyone I hear complaining about their aches and pains. Many just roll their eyes and change the subject, but a few have made snide remarks without even trying them first.

    Well, one of my brother-in-laws was one of those who always had something negative to say. I’m not sure where all that snarkiness was coming from since he hadn’t nor would even try them. That was until 3 days ago. He felt sick and tested positive for covid.

    Earlier on, Gavin had shared with us a protocol to combat that bug. Well, my brother-in-law was in so much pain that he finally accepted to try the blends. His fever had reached 103 and within 30 minutes of taking those blends, his temperature was down to 99.8. He is now a believer!

    Thank you Gavin for always going above and beyond!! You are treasured more than you realize!!!

    So all I can say to those who doubt… try and be amazed of the “magic” of Interstellar Blends!!

  9. Rated 5 out of 5

    Treena Smith

    The Interstellar pain killer blend is amazing!! 🔥The Supernova Interstellar blend is incredible!! 🔥 I’ve suffered from migraine headaches my entire adult life. I was hit by a car at aged 8, that resulted in chronic inflammation in my right leg. Migraines and chronic inflammation are my life and I’ve learned to cope. When I began using Interstellar blends…it was simply out of curiosity. I read the reviews on all the Interstellar blends and wondered if Gavin’s customers were over hyping his products. I purchased Interstellar Supernova and was a given a free sample of the pain killer blends to also try. I wasn’t expecting mind blowing results; my history taught me to tread lightly when it comes to a solution for complete pain eradication.

    Well…it’s been almost a month and I am mesmerized by all of the awesome results of the blends!!!! I can truly say my life has shifted for the better!! My migraine headaches have decreased to a level of zero, my energy has increased, the inflammation in my leg has drastically reduced. The Supernova, specifically has also curved my appetite and made my skin glow. I’ve been feeling extra sexy these days thanks to these blends!! Gavin, thank you for the experience of a life free of headaches and inflammation!! Gavin, you are incredible, gifted and kind!! Thank you for sharing these blends with the world!! ⭐⭐⭐⭐⭐

    I’m now a permanent customer of the Interstellar Blends; I’ve already made my next purchase!

  10. Rated 5 out of 5

    Tony R

    Magical Blend.

    This is long overdue, so, here we go.
    I found out about Interstellarplan from a forex trader named Shaun Lee from one of his ig posts when it was still on. I’m always into natural way of taking care of my own health without involving pharmaceuticals. I used to have headache when I was younger and went to search for natural remedies by looking at my lifestyle and find what is causing the headache. I never even want to take aspirin or pain killer.

    So, long story short, I join Interstellar Blend tele channel and follow the discussions for a good couple of weeks before buying the blends. My first batch consist of Trinity, Rewire, Autonomous, Nebula, Matcha, Senolytic, Apigenin and Seven Sages. I do not set any expectation when taking the very first dose of the blend. But what happen in the next couple of hours was nothing short of MAGICAL. I feel very calm and can direct my focus and attention without fail (and for a long period of time). Everything I do that day feels effortless, everything just flows naturally. No procrastination.

    Then I bought my second batch which consist of pine polen, Rewire, Autonomous, purge, and several other blends. Bear in mind, I’m currently struggling financially but managed to buy the blends – its all about priority. Also, thanks to Gavin’s generosity by giving massive discount continuously. About 50% discount on both orders. So, the “expensive” international shipping becomes negligible.

    Then, 3 weeks ago I bought the third batch which include the Pain Blend (a prototype). This blend is simply another miracle. I took the Pain blend twice a day for 7 days. My back pain (due to HNP) was completely gone. I know this is not a placebo effect as I’ve been having this back pain for more than a decade. Hot yoga has been my go to cure for this back pain to fix the HNP and back bone alignment. Even with hot yoga, I can still feel the pain, although not everyday. The Pain blend completes the puzzle and eradicate the pain completely.

    As a summary, the blend works wonders in many aspects of my life. Health is the primary one. I feel full of energy, don’t feel tired and have great mental clarity. What I write above is not sugar coat, its the reality. By the way, I lost about 6.5kg in 3 months (weight loss is not my goal when buying the blend but I know I will loose weight eventually). Oh . . don’t forget the 22/2 intermittent fasting protocol. I’m doing that too . . super easy.

  11. Rated 5 out of 5

    Totsten Oberacker

    I dont know where to start…
    I was reading many of the information (studies, reviews, product descriptions) for over an year now and was fascinated from the first moment i read all this amazing stuff on Gavins site. He dont want to sell only products, Gavin is looking on the whole thing with every little piece of the puzzle.

    After one year of only looking (i dont had money to spent for at this time) i started with my first order.

    EVERY DOLLAR I SPENT FOR IT WAS BEST INVESTET!!!

    First i was ordering the challenge combo essentials and combined with fasting (i am on vegan keto with fasting for about 3 years now, BUT never had this amazing effects on the wellbeeing ever before).

    Then i took the next step and ordered the stomach reset combo and the january special. MAN, this was the next level stuff i was wishing for the Last years.

    Actually i am waiting for my next order (should be comming these days ;), the 25 mega blend combo, glucose blocker and Jing force

    I NEVER WANT TO MISS THE BLENDS EVER AGAIN

    I feel brain unfogged, amazing, happy, fearless, healthy, gut pain and bloatings are away, psoriasis is over 50% better and is going away week by week, i am selfconfident, stresslevel is down, i love life, less stress with my lovely wife, seeing everything clear and feel the BEST IN MY LIVE I EVER FELT.

    My wife had lost her depression and panic attacks over 90%, stopped her depression-medication, feels amazing, loves the super tonic hair blend and our relationship is better than ever, relaxed and amazing.

    I am a silent reader in the telegram group Gavin made for his custmers… Gavin is a man that stands to his words, helps people from his deepest heart with passion and love, he is loyal, tells the truth without fear.

    He is really a man with a heart of gold and that is what you get when you take his advice and his products.
    Gavin and his blends take the life of me and my lovely wife manu to absolutely lovely perfection.

    I want to thank you from my deepest heart Gavin Robert McGowen
    Thank you, thank you, thank you 🙂

  12. Rated 5 out of 5

    Emily Davidd

    The blends are fantastic— everything they’re advertised as and more. The packaging is pretty too! Gavin answered all my questions promptly and fully— he shared a wealth of knowledge with me and directed me to numerous studies which I appreciate. The blends don’t taste that great, but man do they deliver! Best way to take them is to throw ‘em back like a shot. The only negative thing I can think of is I wish I found Gavin and his blends sooner. Would’ve saved me a lot of time, Frustration, pain, energy and money. His blends are worth every penny.

  13. Rated 5 out of 5

    Suzanne Linskens

    I started the interstellar blends a few years ago. I was sick of running to multiple doctors to figure out solutions to my health issues. I have corrected multiple issues in the past few years by taking the blends Gavin developed. I have corrected my hashimotos disease, eliminated chronic back and knee pain. I add new blends periodically and they are all top notch! Gavin takes years to develop and perfect these blends. I am almost 47 and I have more energy and stamina than I had when I was in my
    20s! The blends are legit…absolutely not “snake oil”.

  14. Rated 5 out of 5

    KT

    Ascendance is absolutely amazing! I received my shipment today and I am beyond speechless. A backstory early this summer I started getting a dull throbbing pain in my scapula area. I thought I had just a sore muscle. I do TRX workouts 4-5 times a week and just kept working out through the pain. This kept getting more irritated but still didn’t think much of it. Fast track to three weeks ago. The pain became unbearable and started shooting down my arm into my fingers. Come to find out it was a pinched nerve in my neck. This pain has been debilitating. It hurt to do everything and let’s face it when you’re in constant pain, you tend to be the not so pleasant being around. The doctors gave me a light muscle relaxer and I could also take Advil which was suggested. I know this is not good on my liver so it was always only if unbearable would I take. I reached out to Gavin and he recommended Ascendance and Spice. I took the Ascendance for the first time today and went about my day. I started to realize there was no throbbing pain anymore. I was not wincing with every movement. I am amazed…shocked. I literally can’t believe it. This is an amazing blend for pain. This is a great tool to help me manage my pain, get through physical therapy and basically enjoy my day again. Thank you for such an awesome product!

  15. Rated 5 out of 5

    Cary Duke

    “Hey you! Yeah, YOU.

    I know you are reading this. I know you what you are thinking.

    Because I had the same thoughts.

    These people posting ridiculous results must be doing something different. Something I can’t do. They must have an unbelievable amount of will power.

    Nope.

    Not even close.

    I’m just like you.

    Probably older and more out of shape than you.

    I DECICED to be healthy. I decided to change my eating and drinking habits.

    That’s it!

    That is the single biggest change I made.

    I decided to be a person who eats healthy, doesn’t drink.

    Results?

    20 days
    21.6lbs lost
    No cravings
    No alcohol (I was a daily drinker for far too long)
    NO acetaminophen (I was up to 4 per day)
    OMAD for 18 days straight with NO hunger or craving issues
    NO pain

    Blends: Trinity, Supernova, Pain Blend 2x day

    ACV, lemon juice and salt 2x day

    That’s it.

    No secret diet. No exercise.

    Nothing hard.

    So, back to you. You still reading?

    You want to make changes in your life?

    Do you have a desire to feel better, have more energy, have no pain?

    Start with deciding to BE that parson.

    Then go live as if you already are that person.

    Last, get Gavin Robert McGowen’s blends. They enhance your decision AND they simply work.”

    ————————

    The pain blend is a winner!

    Stats: Down 15.8lbs. Fasting 22/2. Strict Keto.

    My biggest issue going in was chronic knee pain. It’s been so much better. I can climb the stairs without any pain. More importantly, I can descent the stairs like a normal person. No crab crawling sideways one step at a time.

    My energy level is much improved. My cognitive ability is much improved.

    There has been a tremendous difference in only two weeks.

    Totally Awesome, Gavin Robert McGowen

    Blends taken: Pain, Trinity, SuperNova

    ———–

    PAIN BLEND: “My Report One Full Week:

    Details: 60, very bad knees, overweight. Stairs to my office and bedroom.

    I started doing IF and have moved all the way to 23/1 in a week. No issues with diet. Doing keto. Eating clean. No alcohol. Cut way back on soda (phasing it out).

    Coffee in the am with Trinity, Supernova and the Pain Annihilator. I’m also taking ACV.

    Mid-day a small cup of double chai tea w/blends and ACV

    Eating keto meal when window opens. Hunger is getting less and less during the day. Always manageable. ACV one hour after meal.

    I am down 12.8 pounds. One Week.
    Energy level is increasing.
    Sleep is deeper.

    The biggest noticeable factor?

    There are 2

    The first is awaking w/o feeling pain in the knees.

    The second is walking down the stairs like a normal person ie just walking down them. NO PAIN.

    This is really fantastic!”

  16. Rated 5 out of 5

    Jenny C

    This is an awesome Combo-especially with the Pain Blend included! I was lucky enough to try the Pain Blend for a whole month before it was even released-which I am eternally grateful for. I have pretty severe psoriatic arthritis and was on a lot of medications that were only masking my symptoms and also making me sicker….about a month ago Gavin asked if anyone would like to test the Pain Blend–I JUMPED!! Best decision I’ve made in years. I know it may sound slightly dramatic–but its really not—THIS BLEND CHANGED MY LIFE!!!!! I am OFF all my medicine never to return to it again, I can literally jump out of the bed in the mornings, which I could NOT do even two months ago. Do you understand how awesome that is?? I feel truly Amazing.

    The other Blends are amazing too! I love Nebula-it really helps me at work. I am very shy/Timid and when I take Nebula in the mornings before work…–WOW! Game Changer! People literally don’t “get to me” when I’m on this Blend.

    The other new Blend is Rewire! I had very good results when I first took it-it lights up your Brain. I gave the rest to my mom to help her-and she loves it too! She says it really makes her not as hungry as she normally would be (also makes it where she doesn’t crave ‘bad foods’).

    Trinity was the first Blend I every tried! It helps so much with calming me and my Anxiety. It’ll always hold a special place in my heart.

    Autonomous will help you be laser focused on getting stuff done!

    All the Blends in this package will help you have a better life–in ALL aspects of your Life!!

    ———————-

    My 30 Day Challenge with the Pain Blend ended yesterday!!
    I feel like a different person! Virtually all my pain is gone. I have not been on medication for the full 30 days-and I will NOT be going back to it, because there is no need! The Pain Blend did 100 Times BETTER than any medicine I was ever subscribed!
    My main focus was to get rid of pain(accomplished)—-but as an added bonus I lost 20.6 Pounds!
    Thank you Gavin-so much! Words can’t really express how happy I am!!!!!!!!!!

    ——————-

    Where do I even begin??
    First I would like to say Thank You to Gavin and all of his team for the Amazing Products, Shipping and customer service they provide!
    These Products have improved my whole life…in such a short time! He is the real deal, you can tell him your ailments or what you want to get better at (such as confidence or no anxiety, etc) and he can match you with the best Blends to help you!!

    I have Psoriatic Arthritis and its been getting worse and worse, but luckily Gavin has a Blend for that. 😉 I signed up to do 30 days with the Pain Blend Prototype along with several other blends; happy to say the pain has went away! This alone will make me a customer for LIFE. I am off all of my pain medications for arthritis (which only masked the pain and made me so sick), and replaced it with this particular blend! Its amazing!

    My parents say they see such a difference in me! My moods are better and my mom said she can just “hear in my voice” how much better I am feeling.

    These Blends are truly a LIFE SAVER. I can’t wait to see all the new and exciting things that will be coming out in the next few years.

    YOU owe it to your mind and body to start these Blends and live an Interstellar Life!

    —————–

    Hi Gavin! I’m at my ‘last’ TEN DAYS!! These past 20 days have been awesome! I am back to loving fasting, and I feel so so SO good from the Pain Blend! I really cannot thank you enough!!
    It means the world to me. I love that I am off all my medication (which quite frankly didn’t help much at all-just slightly took the pain edge off) The Pain Blend blows everything I took out of the water!!

  17. Rated 5 out of 5

    Julia Bienkowski, LPC

    Gavin has knocked it out of the park again with his incredible non-opioid pain relieving blend, Ascendance! I have struggled for years with debilitating flare ups of musculoskeletal pain and inflammation and multiple herniated discs as a result of car accident several years ago. I have tried every natural pain relieving supplement to manage the pain, but have never experienced relief so quickly and effectively until Ascendance. After 2 days of taking Ascendance, my back pain was gone entirely and my full range of motion restored. Effective non narcotic pain relief at last! This is truly a miracle product. Thanks Gavin!

  18. Rated 5 out of 5

    Rich Ryan

    Amazing Blend for Pain!
    The folks at Interstellar Blends knock it out of the park again!
    I do big doses of the blends I get to try, as I want to feel the maximum effect. So I did 1/2 tsp of Ascendance (regular dose is 1/4-1/8 tsp) and I could feel the effects within 15 min.
    Ascendance made me feel high and highly positive! It boosted my mood into the clouds.
    I’ve been managing arthritis pain in my hands and ankles for years with Spice and Peel blends (Mom has Rheumatoid and both parents have Osteo Arthritis). With those blends the pain and swelling was down to a minimum. Just mild twinges here and there. With Ascendance however, the pain completely disappeared. I didn’t feel a twinge for the entire 30 days I was on it.
    I’ve also been managing back pain from years of construction work with the blends as well. The stiffness of a morning back was 98% gone with Ascendance. I could barely feel any soreness or stiffness at all. It just vanished! And without any opioids either!
    If you’re getting advanced in years or struggling with chronic pain, you definitely need to try this blend. With this blend it’s back to smooth sailing again!
    Bravo!

  19. Rated 5 out of 5

    Leslie Spry

    My sister, Tonia kept telling me about the blends and told me about Ascendance.
    I’ve been suffering from pain for years and it’s something I thought I would just have to live with, though I was taking pain meds.
    I received my blends on a Friday and started taking them the next day. I felt relief the same day. Within two days I felt a huge difference! I take Ascendance with 2 oz of coffee 3 x per day.
    I Highly recommend Ascendance for anyone suffering with pain and inflammation.

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